Antimicrobial and Antibiofilm Biomaterials Strategies 1

Timeslot: Wednesday, April 27, 2022 - 1:00pm to 2:30pm
Room: Harborside Ballroom A-B, 4th Floor


Treatment of microbial infections is complicated by rising antibiotic resistance and the inherent difficulty of treating biofilm-associated infections. In both scenarios, many current FDA approved antimicrobial drugs are ineffective, leading to a significant health and economic burden. Compounding these issues is a lack of development of new antimicrobial drug classes limiting the pipeline of available therapeutics. Advances in antimicrobial biomaterial therapies have the potential to improve outcomes for bacterial, fungal, viral, and biofilm-associated infections. Innovations in biomaterials are critically needed in the face of the COVID-19 pandemic, both for treatments of the SARS-CoV-2 virus, and also for effective treatment of the severe bacterial and fungal co-infections that have been reported. This session will cover biomaterials approaches to treat bacterial, fungal, and viral infections, including the prevention and eradication of biofilms. Strategies discussed may include antimicrobial surface modifications, device coatings, drug delivery, and immune engineering approaches.


Abstracts will be available for download on April 27, 2022.

  • 1:00:00 PM 1. INVITED SPEAKER: Endowing Face Masks with Virucidal Activity via UV-Grafted Quaternized Cationic Amphiphiles, R. Helen Zha, PhD*(1), Mirco Sorci, PhD(1), Tanner Fink(1), Brigitte Arduini, PhD(1), Katharine Dovidenko, PhD(1), Vaishali Sharma(2), Sneha Singh, PhD(2), Caryn Heldt, PhD(2), Edmund Palermo, PhD(1); (1)Rensselaer Polytechnic Institute, Troy, NY, USA, (2)Michigan Tech University, Houghton, MI, USA

  • 1:30:00 PM 3. Efficacy of saline wash plus antibiotics doped PVA composite in a mouse pouch infection model, David Markel, MD.(1,2), Therese Bou- Akl, MD., PhD.(1,2), Paula Dietz, MS.(1), Bin Wu, MD.(1), Weiping Ren, MD, PhD*(1,3); (1)Ascension Providence Hospital, Southfield, MI, USA, (2)Wayne State University, Detroit, MI, USA, (3)Virotech Co., Inc., Troy, MI, USA

  • 1:45:00 PM 4. Antimicrobial blue light, oregano oil, and CZ gel manage Staphylococcus aureus biofilms at the skin-implant interface of percutaneous osseointegrated prosthetics in an ex vivo setup, Jemi Ong*(1), Rose Godfrey(1), Taylor Peterson(1), Josh Tam(2), Lynn Drake(2), Alexa Nazarian(2), Richard Epperson(1), Brad Issacson(3), Paul Pasquina(3), Dustin Williams(1); (1)University of Utah, Salt Lake City, UT, USA, (2)Wellman Center of Photomedicine, Boston, MA, USA, (3)Uniformed Services University, Bethesda, MD, USA

  • 2:00:00 PM 5. New Fluorinated Polyphosphazene Biomaterials for Controlling Microbial Infections, Shelby Alwine*(1,2), Chen Chen(3), Christopher Siedlecki, PhD(2), Harry Allcock, PhD(3), Lichong Xu, PhD(2); (1)Clarkson University, Potsdam, NY, USA, (2)Penn State College of Medicine, Hershey, PA, USA, (3)The Pennsylvania State University, University Park, PA, USA

  • 2:15:00 PM 6. Antimicrobial Effects of Piezoelectric Charges, Carolina Montoya, PhD*, Santiago Orrego, PhD, Temple University, Philadelphia, PA, USA

Invited Speaker(s)