Biomaterial-Based In Vitro Cancer/Tumor Models for Drug Screening and Diagnostics
Timeslot: Thursday, April 28, 2022 - 1:00pm to 2:30pm
Room: Harborside Ballroom A-B, 4th Floor
Biomaterial-based in vitro cancer/tumor models offer a close mimic of the complex tumor microenvironment, providing versatile platforms for drug and toxicology screening as well as diagnostics. The implementation of these preclinical tools can afford low-cost, easy-to-use systems to evaluate cancer treatments, enhancing the efficacy and toxicological assessment for specific patients, mitigating the limitations of current technologies, and expanding the treatment options and patient’s quality of life.
Abstracts will be available for download on April 27, 2022.
1:00:00 PM 163. INVITED TALK: Tissue engineered organoid models for under- standing longitudinal response to therapy, Alison McGuigan, PhD, University of Toronto
1:30:00 PM 164. Engineering Lung Carcinogenesis Models with Hydrogel-em- bedded Precision-cut Lung Slices, Rachel Blomberg*, Kayla Sompel, Alex Smith, Meredith Tennis, Chel- sea Magin, University of Colorado Denver
Anschutz, Aurora, CO, USA
1:45:00 PM 165. 3D Engineered Prostate Cancer Tissues for in vitro Investigation of Fibroblast Impact on CRPC and ADPC, Nicole Habbit(1)*, Benjamin Anbiah(1), Joshita Suresh(1), Yuan Tian(1), Luke Anderson(1), Megan Davies(1), Iman Hassani(1), Taraswi Mitra Ghosh(1), Balabhaskar Prabhakarpandian, PhD(2), Robert Arnold, PhD(1), Elizabeth Lipke, PhD(1); (1)Auburn University, Auburn, AL, USA, (2)CFD Research Corporation, Huntsville, AL, USA
2:00:00 PM 166. Glioblastoma spheroid responsiveness to chemotherapeutics is influenced by the stiffness of its microenvironment, Joseph Bruns, Silviya Zustiak*, Saint Louis University, Saint Louis, MO, USA
2:15:00 PM 167. Dynamic Tuning of Hydrogel Stiffness & Viscoelasticity to Probe Pancreatic Ductal Adenocarcinoma Cell Behavior, Han Nguyen(1)*, Chien-Chi Lin(2); (1)Purdue University, West Lafayette, IN, USA, (2)Indiana University-Purdue University Indianapolis, Indianapolis, IN, USA