Biomaterial Innovations for Women’s and Children’s Health: Translation from Idea to the Clinic

Timeslot: Thursday, April 28, 2022 - 1:00pm to 2:30pm
Room: Dover A-C, 3rd Floor


Biomaterials research to address problems in the area of women's and children’s health remains underserved, requiring further attention from the scientific community to advance progress in this field. Women’s and children’s health requires a physiologically appropriate approach in the research and development of devices and medical therapies. These requirements are unique and do not lend themselves well to simply adapting those initially designed for adult males, which innovations in biomaterials can address. This session explores research into medical devices, therapeutics, and drug delivery systems specifically targeting the women’s and child health patient population, from research innovation, through prototypes to clinical delivery. This session will stimulate discussion in areas including but not limited to pelvic floor disorders, breast reconstruction, reproductive health and contraception, new fertility treatments, maternal-fetal interface models, and more. The ability to achieve the “bench to bedside” requires a thorough understanding of regulatory requirements for devices, therapeutics and biologics. This session seeks to include discussion on the processes of innovation, development and full clinical implementation to achieve impactful changes in women’s and children’s health


Abstracts will be available for download on April 27, 2022.

  • 1:00:00 PM 157. Fetal Biodistribution of Poly(amine-co-es- ter)-Polyethylene Glycol Nanoparticles for In Ute- ro Gene Therapy, Anna Lynn*, Jinal Pothupitiya, PhD, David Eaton, David Stitelman, MD, Peter Glazer, MD, PhD, W. Mark Saltzman, PhD, Yale University, New Haven, CT, USA

  • 1:15:00 PM 158. Extracellular Matrix-Se- questering and Adhesion Peptide Localization Pro- motes Primordial Follicle Development In Vitro for Fertility Preservation, Ari- ella Shikanov, PhD(1)*, Claire Tomaszewski(1), Daniel Matera, Brendon Baker, PhD(1); (1)University of Michigan, ann arbor, MI, USA

  • 1:30:00 PM 159. Self-fitting Vaginal Stents from Biodegradable, Shape Memory Polymers, Advika Kamatar(1), Andrew Robinson(1), Courteney Roberts(2), Felipe Beltran(2), Jennifer McCracken(3), Julie Hakim(3), Melissa Grunlan(2), Elizabeth Cosgriff-Hernandez(1)*; (1)The University of Texas at Austin, Austin, TX, USA, (2)Texas A&M University, College Station, TX, USA, (3)Baylor College of Medicine, Houston, TX, USA

  • 1:45:00 PM 160. Hormone-Responsiveness of an Endometrial Perivascular Niche in Gelatin Hydrogels, Samantha Zambuto, ScM(1)*, Cody Crosby, PhD(2), Kathryn Clancy, PhD(1), Janet Zoldan, PhD(2), Brendan Harley, PhD(1); (1)University of Illinois at Urbana-Champaign, Urbana, IL, USA, (2)University of Texas at Austin, Austin, TX, USA

  • 2:00:00 PM 161. PEG-PLGA Nanoparticle Distribution in Pregnant Mice Following Vaginal Delivery, N’Dea Irvin-Choy(1)*, Katherine Nelson(1), Jason Gleghorn(1), Emily Day(1,2); (1)University of Delaware, Newark, DE, USA, (2)Helen F. Graham Cancer Center and Research Institute, Newark, DE, USA

  • 2:15:00 PM 162. AMPWIN: Advanced Manufacturing Processes for Women, Infants and Neonatal Health, Henry Forer*, Susan Gilmour, MD, MSc, Robert Burrell, PhD, University of Alberta, Edmonton, AB, Canada