Drug Delivery for Cardiovascular Applications

Timeslot: Friday, April 29, 2022 - 11:30am to 12:30pm
Room: Laurel A-B, 4th Floor


Drug delivery is currently an important part of cardiovascular biomaterials including drug-eluting stents, vascular grafts, cardiac patches, and angiogenesis strategies. However, there are still new biomaterials and controlled release strategies that are needed. Topics of interest include methods to prevent thrombosis, intimal hyperplasia, scar tissue formation, and infection of cardiovascular grafts.


Abstracts will be available for download on April 27, 2022.

  • 11:30:00 269. Fibrin-Specific pNIPAM Nanogels for Targeted Delivery of Fibrino- lytics and Anticoagulants to Treat Thrombotic Complications, Ana Sheridan(1,2)*, Nina Moiseiwitsch(1,2), Emily Mihalko, PhD(1,2), Kimberly Nellenbach, PhD(1,2), Manasi Krishnakumar(1,2), Abhichart Krissanaprasit, PhD(1), Joshua Degennaro(1,2), Jennifer Sollinger(1,2), Jerrold Levy, MD,FAHA,FCCE(3), Brian Cooley, PhD(2), Thom LaBean, PhD(1), Ashley Brown, PhD(1,2); (1)North Carolina State University, Raleigh, NC, USA, (2)University of North Carolina at Chapel Hill, Chapel Hill, NC, USA, (3)Duke University, Durham, NC, USA

  • 11:45:00 PM 270. An Adventitial Painting Modality of Local Drug Delivery to Abate Intimal Hyperplasia, Nisakorn Yodsanit(1,2)*, Takuro Shirasu, MD, PhD(3), Xiujie Xie, MD, PhD(3), Yuyuan Wang, PhD(1,2), Ruosen XIe, PhD(1,2), Yitao Huang(3), Bowen Wang, PhD(3), Lian-Wang Guo(3), K. Kent, MD(3), Shaoqin Gong, PhD(1,2); (1)University of Wisconsin-Madison, Madison, WI, USA, (2)Wisconsin Institute for Discovery, Madison, WI, USA, (3)University of Virginia, Charlottesville, VA, USA

  • 12:00:00 PM 271. nterpenetrating Network Hydrogels for Enhanced Cardiac Retention of Extracellular Vesicles, Selen Uman(1)*, Mark Helmers, MD(2), Noah Weingarten, MD(2), Alexis Schiazza(2), Danika Meldrum(2), Sara Guevara-Plunkett(2), Pavan Atluri, MD(2), Jason Burdick, PhD(1); (1)University of Pennsylvania, Philadelphia, PA, USA, (2)Perelman School of Medicine, Philadelphia, PA, USA

  • 12:15:00 PM 272. Poly[I:C] loaded Liposomes for Pulmonary Arterial Hypertension Treatment, Vidit Singh(1)*, Hu Yang, Laszlo Farkas(2), Hongliang He(3), Jawahar Khetan(1), Da Huang(1), Natalie Hall(1), Lavanya Bhargava(1); (1)Linda and Bipin Doshi Department of Chemical & Biochemical Engineering, Missouri University of Science and Technology, Rolla, MO, USA, (2)Department of Internal Medicine Division of Pulmonary, Critical Care and Sleep Medicine Davis Heart & Lung Research Institute, Ohio State University, Columbus, OH, USA, (3)Department of Chemical and Life Science Engineering, Virginia Commonwealth University, Richmond, VA, USA