Engineered Biomaterials for Neural Applications
Timeslot: Thursday, April 28, 2022 - 2:45pm to 4:45pm
Room: Laurel C-D, 4th
Engineered biomaterials are uniquely positioned for use in creating, testing, and regenerating neural tissue with applications like in vitro models of injury and disease, therapeutic treatments, understanding neural development, and mapping the brain. This session will focus on cutting edge research in neural biomaterials including fundamental material development through pre-clinical studies. These include big questions surrounding understanding and treating diseases and injuries of the peripheral and central nervous systems spanning stem and progenitor cells, neurons, astrocytes, oligodendrocytes, microglia, and Schwann cells.
Abstracts will be available for download on April 27, 2022.
2:45:00 PM 230. INVITED SPEAKER: Engineering Models and Developing Therapies for the CNS, Erin Lavik, ScD, UMBC
3:15:00 231. Activated astrocyte extracel- lular vesicles delivered from MAP promote in situ brain repair after stroke, Shangjing Xin, PhD, Nhi Phan, Lucy Zhang, Tatiana Segura, PhD*, Duke University, Durham, NC, USA
3:30:00 PM 232. Peripheral nerve regeneration using silk fibroin based conducting conduits, Mamatha Pillai, PhD(1)*, Shadi Hoshyar, PhD(2), Rajiv Padhye, PhD(2), Amitava Bhattacharyya, PhD(3); (1)Indian Institute of Technology Bombay, Mumbai, India, (2)RMIT University, Melbourne, Australia, (3)PSG Institute of Advanced Studies, Coimbatore 641004, India, Coimbatore, India
3:45:00 PM 233. Implantation of Human Tis- sue Engineered Nigrostriatal Pathways in a Rat Model of Parkinsonâ€™s Disease, Wisberty Gordián-Vélez(1,2,3)*, Kevin Browne(2,3), James Lim(2,3), Bella Chau(1,2,3), John Duda, MD(3), Rodrigo España, PhD(4), Jason Burdick, PhD(1), H. Isaac Chen, MD(2,3), D. Kacy Cullen, PhD(1,2,3); (1)University of Pennsylvania School of Engineering and Applied Science, Philadelphia, PA, USA, (2)University of Pennsylvania Perelman School of Medicine, Philadelphia, PA, USA, (3)Center for Neurotrauma, Neurodegeneration & Restoration, Philadelphia, PA, USA, (4)Drexel University College of Medicine, Philadelphia, PA, USA
4:00:00 PM 234. A 3D In Vitro Hydrogel Model to Study Oligodendrocyte Progenitor Cell Response to Traumatic Brain Injury, Rachel Mazur(1)*, Ryosuke Yokosawa(2), Pamela VandeVord(2), Kyle Lampe(1); (1)University of Virginia, Charlottesville, VA, USA, (2)Virginia Polytechnic Institute and State University, Blacksburg, VA, USA
4:15:00 PM 235. Non-Viral Gene Editing in Mouse Brain Achieved by Focused Ultrasound via Systemic Delivery, Shuting Cai, MS*, Robin Ji, MS, Nancy Kwon, Joyce Zhou, Yeh-Hsing Lao, Naoto Yoshinaga, Ding Tang, Elisa Konofagou, Kam Leong, Columbia University in the City of New York, New York, NY, USA
4:30:00 PM 236. Designer Hydrogel Delivery of Human Neurons into the Adult Injured Cervical Spine, Vanessa Doulames, PhD(1,2)*, Laura Marquardt, PhD(2), Meghan Hefferon(1,2), James Weimann, PhD(1), Theo Palmer, PhD(1), Giles Plant, PhD(1), Sarah Heilshorn, PhD(2); (1)Stanford University School of Medicine, Stanford, CA, USA, (2)Stanford University School of Engineering, Stan- ford, CA, USA