Immune Cell Interfaces: Immunotherapies, Implants, and Immunobiology
Timeslot: Friday, April 29, 2022 - 1:30pm to 3:30pm
Room: Laurel C-D, 4th Floor
Interfaces with and among immune cells are critical to homeostasis and can lead to the success or failure of new therapies and medical devices. This session aims to shed light on our emerging understanding of immune cell-cell and cell-biomaterial interfacial phenomena and methods to engineer these interactions in order to better diagnose and treat human diseases. Application areas include (but are not limited to): therapeutics (natural and synthetic), diagnostic devices, screening approaches, implants, cell/tissue matrices, bioreactors, modeling, etc.
Abstracts will be available for download on April 27, 2022.
1:30:00 PM 301. Organoid Polymer Functionality and Mode of Bacterial Membrane Antigen Presentation Regulates Ex Vivo Germinal Center Epi- genetics and Early Memory B Cell-Like Response, Pamela Graney(1), Zhe Zhong(2), Sarah Post(1), Ilana Brito(1), Ankur Singh(2)*; (1)Cornell University, Ithaca, NY, USA, (2)Georgia Institute of Technology, Atlanta, GA, USA
1:45:00 PM 302. Multivalent, T Cell-Engaging Cytokines for Leukemia Immunotherapy, Erik Dreaden, PhD*, Emory School of Medicine, Georgia Institute of Technology, Children’s Healthcare of Atlanta, Atlanta, GA, USA
2:00:00 PM 303. Immunometabolic Approaches to Mitigating Formation of the Foreign Body Response Capsule, Sabrina Macias*, Olivia Palmer, Arun Wanchoo, PhD, Gregory Hudalla, PhD, Benjamin Keselowsky, PhD, University of Florida, Gainesville, FL, USA
2:15:00 PM 304. Discovery of Vomocytosis by Cryptococcus neoformans in Dendritic Cells, Jamal Lewis*, PhD, Noah Pacifici, Agustina Diener, Melissa Cruz-Acuña, PhD, Neeraj Senthil, Hyunsoo Han, University of California, Davis, CA, USA
2:45:00 PM 305. Host type-2 immune response to xenogeneic serum proteins impairs biomaterial-directed cell therapy, Andrés García, PhD, Rebecca Schneider, Pranav Kalelkar, PhD, Hannah Theriault, María Coronel, PhD, Karen Martin*, Georgia Institute of Technology, Atlanta, GA, USA
3:00:00 PM 306. Macrophage Activation in Response to Shape-memory Polymer Coated Embolization Coil Devices, Sarah Chau, Scott Herting, Dillon Noltensmeyer, Hamzah Ahmed, Duncan Maitland, Shreya Raghavan*, Texas A&M University, College Station, TX, USA
3:15:00 PM 307. Activation of Canonical Wnt Signaling Primes Pro-inflammatory Macrophage Polarization in Response to Titanium Physicochemical Cues, Derek Avery*, Loc Bui, Jefferson Abaricia, Arth Shah, Lais Morandini, PhD, Rene Olivares-Navarrete, PhD, Virginia Commonwealth University, Richmond, VA, USA